Pantethine is the stable, metabolically active form of pantothenic acid, or vitamin B5.
Pantethine is a vital component of coenzyme A, a cofactor for dozens of enzymatic reactions, including those involved with fat and carbohydrate metabolism. Clinical trials suggest that, because its biochemical configuration is closer to coenzyme A than pantothenic acid,
Pantethine may have more benefit than pantothenic acid.
Pantethine appears to help metabolize fatty acids by activation of coenzyme A, promotion of carnitine transport of fatty acids into the mitochondria, and subsequent intra-mitochondrial oxidation of fatty acids. All of these help improve energy production in every cell of the body.
Consequently, pantethine supplementation has been found to support good cardiovascular health. In addition, increases in beneficial HDL cholesterol and apolipoprotein A1 have been noted in association with
Pantethine supplementation. Apolipoprotein A1 is the major protein component of HDL and promotes cholesterol removal from tissues to the liver for excretion.
Pantethine is also considered the "anti-stress" vitamin because it supports healthy adrenal cortex function and hormone synthesis, particularly during times of stress. Pantothenic acid deficiency can result in adrenal atrophy, which is characterized by increased fatigue, sleep disturbances, nausea, and abdominal discomfort.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.
