Silybum marianum (milk thistle) has been used for centuries to support liver function. Silymarin's hepatoprotective effects are accomplished via several mechanisms, including antioxidation, inhibition of lipid peroxidation, enhanced liver detoxification via inhibition of phase I detoxification and enhanced glucuronidation, and protection of glutathione depletion. Siliphos consists of the most potent flavonoid in silymarin (silybin) bound to phosphatidylcholine for enhanced hepatoprotection and bioavailability.
Curcumin, an active flavonoid from turmeric, has potent antioxidant, hepatoprotective, and gastroprotective properties. Curcumin is bound to phosphatidylcholine in the highly bioavailable phytosome complex – Meriva.
Cynara scolymus (artichoke) has a long history of use in hepatic support.
Picrorhiza is used in Ayurvedic medicine to optimize liver function. In studies, Picrorhiza extracts and their constituents protected liver cells from damage caused by carbon tetrachloride, aflatoxin B1, and acetaminophen. Picrorhiza acts as an antioxidant and inhibitor of lipid peroxidation in cell membranes, and it also increases bile flow. The hepatoprotective effects of Picrorhiza may be due to its antioxidant activity – inhibition of oxygen anion generation and free-radical scavenging. Like silymarin, Picrorhiza can stimulate liver regeneration, possibly via stimulation of nucleic acid and protein synthesis.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.
